What are NSAIDs and how do they work?

Non-steroidal anti-inflammatory drugs (NSAIDs) are non-prescription, over-the-counter pain relievers such as aspirin, ibuprofen, and naproxen sodium. They are popular treatments for muscular aches and pains, as well as arthritis.

NSAIDs not only relieve pain, but also help to decrease inflammation, prevent blood clots, and reduce fevers. They work by blocking the actions of the cyclooxygenase (COX) enzyme. There are two forms of the COX enzyme. COX-2 is produced when joints are injured or inflamed, which NSAIDS counteract. COX-1 protects the stomach lining from acids and digestive juices and helps the kidneys function properly. This is why side effects of NSAIDs may include nausea, upset stomach, ulcers, or improper kidney function.

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American Orthopedic
& Sports Medicine
30 West Century Road
Suite 320
Paramus, NJ 07652
(201) 261-2000

New Jersey's Best

Dr. Steven Stoller's Bergen County, New Jersey practice specializes in physical therapy, sports medicine and orthopedic knee pain and shoulder pain.

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If you are in Bergen County or the greater New Jersey area, contact Dr. Stoller's office to schedule an appointment with New Jersey's best sports medicine doctor. For directions to our Bergen County, NJ office, click here.